The Novel Concept and Treatments for Cancer
"Seed Knife" Therapy

"Seed Knife" Therapy
- "Seed-knife" is a brachytherapy with implantation of radioactive seeds. The 125Iodine seed which is often used has a half -life of 59 days and releases short-course of gammaray. The seeds implanted into cancerous masses and nearby tissue radiate targeted cells and ultimately destroy cancer.
- According to images offered by ultrasound, CT or MRI, using computational optimization techniques, a three-dimensional conformal treatment planning is made for making dose calculation. Then the number and location of seeds implanted is calculated.
- Seed implantation is often performed percutaneously under guidance of ultrasound or CT, as well as by direct viewing during the operation.
Advantages
Seed therapy is a local radical ablation, hence it will not harm the whole body
- The seed can neither be absorbed by body nor excreted to out of it. Therefore it is not harmful to surrounding people and environment
- There are no major side effects which are developed in traditional chemo/radiotherapy
- Seed implantation can be performed percutaneously and is a miniinvasive modality
Indication
- As a primary or supplementary modality, seed implantation can be used for: prostate cancer, tumors of soft tissue (sarcoma), brain cancer (glioma), breast cancer,pancreatic cancer,liver cancer,tongue cancer,oral cancer, pharyngeal cancer, nasopharyngeal cancer, cervical cancer, ovary cancer, thyroid cancer, metastatic lymph nodes.
- The technique is for eradication of unresectable or residue lesions during or after operation, as well as for prevention of cancer recurrence.
- There is a synergistic effect of a combination of seed implantation with cryosurgery
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