The Novel Concept and Treatments for Cancer
 Alcohol Injection Ablation
Alcohol Injection Ablation
Principle
The pure alcohol (i,e,ethanol) induces tumor destruction by drawing water out of the tumor cells (dehydrating them) and denaturing the structure of the cellular proteins?resulting in complete ablation of the tumor.
Technique
The 100? alcohol is injected through the skin (percutaneously) into the tumor using a very thin needle under the guide of ultrasound or CT. It may take up to five or six sessions of injections to completely destroy the cancer.
Indication
Alcohol injection may be appropriate for patients with any of the following:
- a single of lesion smaller than 5 cm in diameter
- up to three lesions smaller than 3 cm in diameter that are localized but unresectable due to the location in the liver, and concomitant medical considerations (cirrhosis)
- a lesion surrounded by a shell consisting of scar tissue (fibrous encapsulation) and not near the surface of the liver cancer
Tumor Response
Tumor response rates to alcohol injection have been reported to be 90? 100% in liver cancer smaller than 2cm in diameter, 70% in liver cancer of 3cm in diameter, and 50% in 5cm in diameter.
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